Table of Contents - Schizophrenia Biology
- Schizophrenia Researchers
- Introductory Presentation on the Biology of
Schizophrenia
- Reports on Schizophrenia
- Schizophrenia as a Model of Dopamine Dysfunction
- Top Papers, Journals, Researchers and Institutions
focused on Schizophrenia
- Other Papers on Genetics and Mental Illness
- Some of the Current Areas of Focus
in Schizophrenia Research
- Internet-based Schizophrenia Video
Lectures and Presentations
- Recommended
Advanced Books on the Biology of Schizophrenia
- Recommended Professional Books
on Schizophrenia and Psychiatric Drugs
- Types of Schizophrenia and Related
Illnesses
- Schizophrenia Genetics, Research
Organizations, and Related Information
- The
Latest Schizophrenia Biology News
- The
Latest Schizophrenia Research News and Journal Article Summaries
- Schizophrenia Researchers -
Following is a list of some of the researchers who are helping most
to advance the science as well as the public understanding of schizophrenia.
Its an exciting time in schizophrenia biology and genetics today - with
advancements and research papers on many new genes involved in schizophrenia
coming out on a monthly basis. The work being done by "Decode Genetics,
Inc." in particular seems to be some of the most forward looking
and progressive. Decode's work represents the first time a gene has
been identified by two independent studies to be associated with schizophrenia.
- Dr. E. Fuller Torrey - Stanley Medical Research Institute
- Nancy C. Andreasen - University of Iowa
- Dr. Kari Stefansson, Founder, Decode
Genetics, Inc. (Iceland)
- Dr. Irv Gottesman - University of Virginia
- Dr. Tom McGlashan & Dr. Scott Woods (Yale University)
- Dr. March Shelton - Harvard University
- Dr. Ann Pulver - Johns Hopkins University
- Dr. Tonmoy Sharma - Institute of Psychiatry (London, UK)
- Dr. Peter McGuffin
- Dr. Daniel R. Weinberger
- More
Very Good Interviews with Schizophrenia Researchers
- Introductory
Presentation on the Biology of Schizophrenia
- Reports on Schizophrenia
- A Neurological Basis for Poor Insight
in Schizophrenia - Review of the Research (paper
for an advanced neuroscience research seminar, Dec 2004. HTML File)
- Recent advances in understanding
mental illness and psychotic experiences - Year 2000,
300K PDF File, ( A report by The British Psychological Society, Division
of Clinical Psychology)
- Early Psychosis
Treatment Guide - Year 2002, University of British
Columbia - Note: this is a large (3 MB) PDF file
and it may take a few minutes to download if you have a slow internet
connection).
- Lecture: Exploring the Mind and
Brain in Health and Disease (by Nancy Andreasen)
- Schizophrenia
as a Model of Dopamine Dysfunction
(Excerpt
from Timmons and Hamilton textbook) Note: this textbook
excerpt is rather old (1990) but still a very good introduction to the
biology of schizophrehia. See the videos and recommended reading below
for more current information on the biology and genetics of schizophrenia.
- Some of the Current Areas of Focus in Schizophrenia
Research
- Internet-based Schizophrenia Video Lectures
and Presentations - 2002, 2003, 2004 (Note: Please
email us with more links
like these below, if you find any). Note, many of the videos below are
extremely good - however you frequently have to suffer through a long
and boring (5 to 10 minute) introduction. Once you get past all the
dedications to all the school's administrators, etc, things get interesting
very quickly. Well worth the time if you want to learn the state of
the art in these areas. These are high-bandwidth (high quality) videos
so for best viewing you should watch this from work or school where
the Internet connection is fast (DSL, cable or faster). Just click on
the link that you're interested in to start the download. If you're
on a Macintosh (or want the best quality video available on a PC) -
you'll need a "Real Audio" player. Download
a free copy from this link.
- Internet-based Schizophrenia Lecture Videos and Presentations from
UCLA- 2003/2004
- "Nicotinic
Receptors and Schizophrenia"
Robert Freedman, M.D., Professor and Chair, Department
of Psychiatry, University of Colorado School of Medicine, Denver VA
Medical Center, This presentation is supported by an unrestricted
educational grant from Eli Lilly & Company
- "Mapping
Brain Changes in Alzheimers Disease,Schizophrenia, and Development"
Paul Thompson, Ph.D. Associate Professor of Neurology, Laboratory
of Neuroimaging, Department of Neurology, Brain Mapping Center, UCLA
Neuropsychiatric Institute, University of California, Los Angeles,
Geriatric Mini-Series
- "Suicidal
Behavior in Patients with Schizophrenia and Schizoaffective Disorder"
Vinod Kumar, M.D. , Executive Director, Neuroscience
Clinical Development , and Medical Affairs , Novartis Pharmaceuticals,
Clinical Professor of Psychiatry, University of Illinois, Chicago
This presentation is supported by an unrestricted education grant
from Novartis AG
- "Parental
Mental Illness and Its Impact on Children"
Stephen P. Hinshaw, Ph.D. , Professor and Chair-designate
, Department of Psychology , University of California, Berkeley.
- "How
Pharmaceutical Companies Mold our Perceptions of Mental Illness"
David Healy, M.D., F.R.C. Psych Director , North Wales
Department of Psychological Medicine , University of Wales, Great
Britain . Held in Collaboration with the Neuroscience History Archives
and the Center for History, Culture, and Neuroscience (both of the
BRI) and Medical History.
- Psychopathology
and Drug Discovery for Schizophrenia - William
T. Carpenter, Jr., M.D., Professor of Psychiatry and Pharmacology,
University of Maryland School of Medicine, Director, Maryland Psychiatric
Research Center
- "Treatment
of First Episode Schizophrenia" Rona Hu, M.D.,
Assistant Professor , Department of Psychiatry and Behavioral Sciences,
Medical Director, Acute Psychiatric Inpatient Unit, Stanford University
School of Medicine
- "A
Comparison of Metabolic Effects of Antipsychotic Medications",
Donna Wirshing, M.D., Associate Professor UCLA Department
of Psychiatry and Biobehavioral Sciences, Co-chief, Schizophrenia
Treatment Unit, West LA Veterans Administration Medical Center
- "Mechanisms
of Action of Antipsychotics", Jeffrey Lieberman,
M.D., Vice Chairman of Psychiatry, Professor Department of Psychiatry
and Pharmacology, University of North Carolina School of Medicine
- "Treatment
of Psychosis: When Outcomes are Suboptimal", James
Jefferson, M.D., Distinguished Senior Scientist, Madison Institute
of Medicine, Inc.
- "Psychiatric
Genetics: A Current Perspective", Kenneth
S. Kendler, M.D., Director, Virginia Institute for Psychiatric and
Behavioral Genetics
- "The
Anatomy of Attention and Schizophrenia", Robert
Bilder, Ph.D., Visiting Professor, Psychiatry and Biobehavioral Sciences,
Chief, Medical Psychology-Neuropsychology, Neuropsychiatric Institute,
David Geffen School of Medicine, University of California, Los Angeles
- "Clinical
Effectiveness of Atypical Antipsychotics in Naturalistic Trials",
Steven Potkin, M.D., Professor, Psychiatry and Human
Behavior, Director, Clinical Research, Director, Brain Imaging Center,
University of California, Irvine
- "Antipsychotics
in Special Populations: Pediatrics and Adolescents", James
J. McGough, M.D., Associate Professor, Clinical Psychiatry, Neuropsychiatric
Institute, David Geffen School of Medicine, University of California,
Los Angeles
- Internet-based Schizophrenia Lecture Videos and Presentations - 2001/2002
- "The
Revolution in Psychiatric Genomics: The Coming Era of New Treatments
and Diagnoses"
John Kelsoe, M.D., Associate Professor of Psychiatry,
University of California, San Diego
- "Cognitive
Determinants of Work Status in Schizophrenia" ,
Susan McGurk, Ph.D., Assistant Professor of Psychiatry, Mt. Sinai
School of Medicine, New York
- "Long
Term Metabolic Consequences of Atypical Antipsychotic Agents"
, William C. Wirshing, M.D., Professor of Psychiatry,
UCLA Department of Psychiatry and Biobehavioral Sciences
- "Schizophrenia
in Late Life: What is New and What is Old?", Dilip
V. Jeste, M.D., Professor of Psychiatry and Neurosciences, Chief,
Geriatric Psychiatry Division, University of California, San Diego
- "Update
on the Long-term Treatment of Schizophrenia - Presentation",
Stephen R. Marder, M.D., Professor, Vice-Chair, Department
of Psychiatry, University of California, Los Angeles, VA Medical
Center
- "Update
on the Long-term Treatment of Schizophrenia - Presentation",
Stephen R. Marder, M.D., Professor, Vice-Chair, Department
of Psychiatry, University of California, Los Angeles, VA Medical
Center
- "Clinical
Management of Psychosis: The Short- and the Long-term - Discussion",
Ira Glick, M.D., Professor of Psychiatry and Behavioral
Sciences, Director, Schizophrenia Clinic, Stanford University School
of Medicine
- "New
and Newer Mechanisms of Action for Antipsychotic Medications- Presentation"
Carol Tamminga, M.D., Professor of Psychiatry
and Pharmacology, Maryland Psychiatric Research Center, University
of Maryland School of Medicine
- "New
and Newer Mechanisms of Action for Antipsychotic Medications - Discussion"
Carol Tamminga, M.D., Professor of Psychiatry
and Pharmacology, Maryland Psychiatric Research Center, University
of Maryland School of Medicine
- "Functional
Outcomes in Schizophrenia: Activities and Social Relations - Presentation",
Joseph P. McEvoy, M.D., Associate Professor, Department of Psychiatry
and Biobehavioral Sciences, Duke University Medical Center
- "Functional
Outcomes in Schizophrenia: Activities and Social Relations - Discussion",
Joseph P. McEvoy, M.D., Associate Professor, Department
of Psychiatry and Biobehavioral Sciences, Duke University Medical
Center
- "Early
Detection and Intervention in Schizophrenia" - Dial
Up Version (from UCLA, 2001 presentation)
- "Early
Detection and Intervention in Schizophrenia" - Broadband Version,
Thomas H. McGlashan, M.D., Professor, Department
of Psychiatry, Yale University School of Medicine, Yale Psychiatric
Institute, New Haven, Connecticut.
More Info: All the above video lectures are from UCLA's
professional education web site
More Vidoes related to schizophrenia and treatment:
The
New York State Office for Mental Health - Conference Videos (2001)
Recommended Advanced Books on
the Biology of Schizophrenia
These books cover the science, biology and genetics of schizophrenia.
"Nature via Nurture", while not specifically a book about schizophrenia
- has an entire chapter (Chapter 4 - The Madness of Causes) on the genetics
and environmental influences of schizophrenia. Overall, the book is a
well-written and very enjoyable book about the interplay of genes and
environment in human development. Dr. Nancy Andreason's and Dr. Irv Gottesman's
books are good in-depth college-level books covering schizophrenia by
two of the leading researchers that are focused on schizophrenia.
Nature
Via Nurture : Genes, Experience, and What Makes Us Human by Matt
Ridley (Author), Publisher: HarperCollins; (April 29, 2003) ISBN: 0060006781
Psychiatric
Genetics and Genomics by Peter McGuffin (Editor), Michael J Owen
(Editor), Irving I Gottesman (Editor), Publisher: Oxford University
Press; (December 2, 2002), ISBN: 0192631489
Brave New Brain: Conquering Mental Illness in the Era of the Genome
by Nancy C. Andreasen, Publisher: Oxford University Press; (April 2001)
ISBN: 0195145097 (HARDCOVER) "Excellent introductions to
neuroscience, brain imaging, and genetics. Outstanding overviews of
what is known about the neuroscience and genetics of the major psychiatric
disorders of schizophrenia, mood disorders, dementia, and anxiety disorders.
The descriptions of the history and neuroscience of medication are especially
good."--Nature
Brave
New Brain: Conquering Mental Illness in the Era of the Genome by
Nancy C. Andreasen , Publisher: Oxford University Press; (February
2004), ISBN: 0195167287, (SOFTCOVER)
Schizophrenia
Genesis: The Origins of Madness by Irving I. Gottesman, Publisher:
W H Freeman & Co.; (November 1990) ISBN: 0716721473
The
BROKEN BRAIN by Nancy C. Andreasen (Author), Publisher: Perennial;
Reprint edition (November 1985) ISBN: 0060912723 (Note: this is an old
book -- over 15 years old -- and should only be referenced if the more
recent books listed above are not available. Information in the field
of genetics is progressing rapidly, and a book that is 15 years old
is truly ancient).
Recommended Professional Books on Schizophrenia
and Psychiatric Drugs
Psychiatric
Genetics and Genomics by Peter McGuffin (Editor), Michael J Owen
(Editor), Irving I Gottesman (Editor), Publisher: Oxford University
Press; (December 2, 2002), ISBN: 0192631489
Practice
Guidelines for the Treatment of Patients with Schizophrenia by American
Psychiatric Association, APA, Publisher: Amer Psychiatric Pr; 1st edition
(January 15, 1997) ISBN: 0890423091. Developed by experts on schizophrenia
and exhaustively reviewed by APA members, the American Psychiatric Association
Practice Guideline for the Treatment of Patients With Schizophrenia
provides therapists with a set of patient care strategies that will
aid their clinical decision making. Note: This publication is usually
available on-line for free at: http://www.psych.org/clin_res/pg_schizo.cfm
Serious
Mental Illness and the Family: The Practitioner's Guide by Diane
T. Marsh, Publisher: John Wiley & Sons; 1 edition (October 2, 1998)
ISBN: 0471181803
Schizophrenia
by Steven R. Hirsch (Editor), Daniel R. Weinberger (Editor), Penny R.
Mitchell, Publisher: Blackwell Publishers; 2nd Revision edition (March
2003) ISBN: 0632063882
Comprehensive
Care of Schizophrenia by Lieberman, Publisher: Martin Dunitz Ltd;
(December 2001) ISBN: 1841841501
Schizophrenia
and Mood Disorders: The New Drug Therapies in Clinical Practice By
Peter F. Buckley (Editor), John L. Waddington (Editor), Publisher: Edward
Arnold; 1st edition (February 15, 2000) ISBN: 0750640960
Insight
and Psychosis by Xavier F. Amador (Editor), Anthony S. David (Editor),
David Amador, Publisher: Oxford University Press; (January 1998) ISBN:
0195084977
Distinguishing
Psychological From Organic Disorders: Screening for Psychological Masquerade
by Robert L., Md. Taylor, Publisher: Springer Pub Co; 2nd edition (July
15, 2000) ISBN: 082611329X
The
Schizophrenias: A Biological Approach to the Schizophrenia Spectrum
Disorders (Springer Series on Psychiatry) by Mary Coleman, Christopher
Gillberg, Publisher: Springer Pub Co; (September 1996) ASIN: 0826192904
Genetics
and Mental Illness: Evolving Issues for Research and Society by
Laura Lee Hall (Editor), Publisher: Plenum Pr; (January 1996) ISBN:
0306451662
Treating
Schizophrenia (Jossey-Bass Social and Behavioral Science Series)
by Werner M. Mendel, Publisher: Jossey-Bass; 1st Edition edition (June
1989) ASIN: 1555421512
Types of Schizophrenia and Related Illnesses
Schizophrenia Genetics, Research Organizations,
and Related Information
- Schizophrenia Genetics
- Database
for Schizophrenia candidate genes - "The Database for Schizophrenia
candidate genes focusing on Variations(VSD) includes the genes that
contains polymorphisms related with schizophrenia. Has also information
about the metabolic pathways in an easy-to-use interface."
- The Costs of Schizophrenia/Mental Illness
- Worldwide Prevalence of Mental illness
Research Funding Organizations
- Schizophrenia Research Centers (a sample, in no particular order)
- USA Schizophrenia Research Centers
- Canadian Schizophrenia Research Centers
- Research Symposiums and Events
- Schizophrenia Related Research Journals
- Schizophrenia Scientific and Professional Organizations
- Companies/Organizations Researching the Genetic Causes of Schizophrenia
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