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November 13, 2006Remission in Early Psychosis: A StudyData from 462 patients with first-episode psychosis who participated in a multinational, randomized, double-blinded trial of risperidone and haloperidol over 2 to 4 years were studied to glean more information about rates of remission and predictors of remission. The study used remission criteria, as defined by "The Remission in Schizophrenia Working Group", consisting of a reduction to mild levels on key symptoms for at least 6 months. Remission criteria for the required 6 months were met by 23.6% of the 462 patients (109). Researchers found that the two strongest predictors of remission were:
See Also: Remission in Schizophrenia: Proposed Criteria and Rationale for Consensus Am J Psychiatry 162:441-449, March 2005 Additional Reading: Posted by Jeanie Wolfson at November 13, 2006 11:19 AM
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What I find disturbing about this study is leaving patients on a medication for 2-4 years without remission, instead of trying different meds.
-Naomi
Posted by: Naomi_njw at November 13, 2006 11:46 AM
They seem to be intentionally including briefer psychoses and schizophreniforms without factoring in diagnostic instability, in order to provide a high remission rate result in their study.
Posted by: slc at November 17, 2006 04:17 AM