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September 13, 2007New York: Treatment-Resistant Schizophrenia Research Participation OpportunityRead more... Schizophrenia Research Participation
The New York State Psychiatric Institute is doing research on a new treatment for treatment resistant psychosis and are looking for participation from people who meet the following criteria. The three-month program is free, and is onsite at the institute. Following is the email we received from them: We are looking for volunteers for a NARSAD funded study of IV Ceftriaxone (Rocephin) for refractory (treatment resistant) psychosis. We are looking for people aged 18-45, diagnosed with Schizophrenia or Schizoaffective disorder, who have been treated with at least 3 different antipsychotic medications and are still experiencing significant symptoms. This study compares the effectiveness of intravenous placebo (inactive drug) with the intravenous antibiotic Ceftriaxone. This is an inpatient study and participants will be hospitalized at the New York State Psychiatric Institute for 2-3 months at no cost to the participant. Ceftriaxone has been shown to reduce psychotic symptoms (auditory hallucinations and delusions) in a small number of people with a history of Lyme disease. This study is trying to see if Ceftriaxone can be helpful for people who have similar symptoms without Lyme disease. To Participate: Please contact Katy Harper (212) 543-5422 for more information. email: harperk@nyspi.cpmc.columbia.edu Posted by szadmin at September 13, 2007 12:41 PM
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I find this research very interesting as I feel that in the main the current pharmaceutical industry is somewhat shortsighted, or not creative enough to look beyond "atypical antipsychotics" - how many god damn d2/5ht2 drugs do we need.
They should be trying altogether different approaches looking for drugs many already in use for other things that work as antipsychotics but by different mechanisms ie not obvious receptor blockers. Examples include drugs to treat parasitic infections antibacterial and antiviral, antioxidants, innate antipsychotics such as anandamide and extracts from natural drugs such as those used by indigenous populations such as betel nuts.
Posted by: Matt at September 14, 2007 07:03 AM